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A collaborative project between 3D image analysis software company Lume VR Ltd. and scientists at the University of Cambridge showed off a new virtual reality tool today that gives scientists a new view of the inner workings of human cells.

The researchers hope the Google Street View-style tool will provide an up close and personal way to understand fundamental problems in biology to help new treatments for disease. The details are published in the scientific journal “Nature Methods.”

By using VR, scientists can “walk” through the “byways” and “highways” within the cells themselves and see proteins fold and unfold. They also can potentially see where things go wrong when they go wrong and even rewind biological processes by looking through recorded and visualized datasets.

The software, vLUME, uses super-high-resolution microscopy data that is collected, collated and digested. After that, the data needs to be rendered in a manner understandable by

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IMAGE

IMAGE: DBScan analysis being performed a mature neuron in a typical vLUME workspace.
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Credit: Alexandre Kitching

Virtual reality software which allows researchers to ‘walk’ inside and analyse individual cells could be used to understand fundamental problems in biology and develop new treatments for disease.

The software, called vLUME, was created by scientists at the University of Cambridge and 3D image analysis software company Lume VR Ltd. It allows super-resolution microscopy data to be visualised and analysed in virtual reality, and can be used to study everything from individual proteins to entire cells. Details are published in the journal Nature Methods.

Super-resolution microscopy, which was awarded the Nobel Prize for Chemistry in 2014, makes it possible to obtain images at the nanoscale by using clever tricks of physics to get around the limits imposed by light diffraction. This has allowed researchers to observe molecular processes as they happen.

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